Our research is directed at understanding the integrative physiology of cardiovascular and metabolic control, at the whole-organism level. Ongoing projects are investigating the tissue-specific roles of the renin-angiotensin system in the control of blood pressure and resting metabolic rate; the role of neurohormones in the pathogenesis of the pregnancy-specific cardiovascular disorder "preeclampsia"; and the physiological relevance and mechanisms which control 'non-aerobic' metabolic processes in vivo. Ultimately our work is aimed at identifying novel therapeutic targets for hypertension, preeclampsia, obesity, and diabetes.

Justin Grobe
Research Projects Lab Members In the News
Learn more about the laboratory's active research projects with detailed descriptions of each. Meet both the current and former members of the laboratory and their contact information. Read more about lab members and lab advances featured in the media.